Phenotypic and functional characterization of the CD6-ALCAM T-cell co-stimulatory pathway after allogeneic cell transplantation
CD6 is a co-stimulatory receptor expressed on T cells that binds activated leukocyte cell adhesion molecule (ALCAM), Dental expressed on antigen presenting cells, epithelial and endothelial tissues.The CD6-ALCAM pathway plays an integral role in modulating T-cell activation, proliferation, and trafficking.In this study we examined expression of CD6